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光固化玻璃离子水门汀和复合体水门汀的成分释放

Component release from light-activated glass ionomer and compomer cements.

作者信息

Hamid A, Okamoto A, Iwaku M, Hume W R

机构信息

Department of Resorative Dentistry, University of California, San Francisco, CA, USA.

出版信息

J Oral Rehabil. 1998 Feb;25(2):94-9. doi: 10.1046/j.1365-2842.1998.00247.x.

Abstract

The purpose of this study was to identify and quantify any component released from seven commercially available light-cured or resin-modified glass ionomer and compomer cements. Twenty-one separate cylindrical stainless steel moulds 6 mm in diameter and 1.0 mm deep were filled with one of seven glass ionomer or compomer cements, light activated and then immediately immersed in separate containers of distilled water. Water samples were retrieved over a time period of up to 30 days and retained for analysis. An occlusal cavity 6 mm in diameter was prepared in extracted human third molar teeth with a remaining dentin thickness of 1.6-2.0 mm. A polypropylene chamber was attached to the cemento-enamel junction of each tooth to contain 1 mL of distilled water. Ten teeth were each filled with one of three cements and light activated. Water samples (eluates) were retrieved over a period of time. All samples were analysed by high performance liquid chromatography. Only one component, hydroxyethyl methacrylate (HEMA), was detected in the eluates from both tooth and mould samples. Analysis of diffusion of the HEMA through dentin showed a relatively sustained movement into the pulp space during the first day, with exponential decline thereafter. Our data show that HEMA was released from all of the light activated glass ionomer cements studied and from the compomer, both directly into water and through dentin. This release may be relevant both to the risk of adverse pulpal responses in patients and to the risk of allergy in patients and dental personnel.

摘要

本研究的目的是识别和量化七种市售光固化或树脂改性玻璃离子水门汀和复合体水门汀释放的任何成分。将二十一个单独的直径6毫米、深1.0毫米的圆柱形不锈钢模具分别装满七种玻璃离子水门汀或复合体水门汀中的一种,进行光固化,然后立即浸入单独的蒸馏水瓶中。在长达30天的时间段内采集水样并留存用于分析。在拔除的人类第三磨牙上制备直径6毫米的咬合洞,剩余牙本质厚度为1.6 - 2.0毫米。在每颗牙齿的牙骨质 - 釉质界处连接一个聚丙烯腔室,以容纳1毫升蒸馏水。十颗牙齿分别用三种水门汀中的一种填充并进行光固化。在一段时间内采集水样(洗脱液)。所有样品均通过高效液相色谱法进行分析。在牙齿和模具样品的洗脱液中仅检测到一种成分,即甲基丙烯酸羟乙酯(HEMA)。对HEMA通过牙本质的扩散分析表明,在第一天期间它相对持续地向牙髓腔移动,此后呈指数下降。我们的数据表明,HEMA从所有研究的光固化玻璃离子水门汀以及复合体中释放出来,既直接释放到水中,也通过牙本质释放。这种释放可能与患者牙髓不良反应的风险以及患者和牙科工作人员的过敏风险都相关。

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