Esteban-Redondo I, Innes E A
Moredun Research Institute, Edinburgh, U.K.
Comp Immunol Microbiol Infect Dis. 1997 Feb;20(2):191-6. doi: 10.1016/s0147-9571(96)00039-2.
Toxoplasma gondii is a protozoan parasite that can infect all warm-blooded animals. Sheep and cattle show different susceptibilities to T. gondii infection. Primary infection in pregnant sheep can result in abortion or the birth of weak lambs but they are then protected against further challenge by the development of an effective immunity. Cattle on the other hand can be readily infected, but abortion or perinatal mortality have not been recorded. The evidence suggests that cattle develop a more effective immune response to T. gondii infection than sheep. Potential mechanisms to explain these differences are discussed in this paper.
刚地弓形虫是一种可感染所有温血动物的原生动物寄生虫。绵羊和牛对刚地弓形虫感染表现出不同的易感性。怀孕母羊的初次感染可导致流产或产出体弱的羔羊，但随后它们会通过产生有效的免疫力来抵御进一步的感染。另一方面，牛很容易被感染，但尚未记录到流产或围产期死亡的情况。有证据表明，牛对刚地弓形虫感染产生的免疫反应比绵羊更有效。本文讨论了解释这些差异的潜在机制。
