Charlebois R L, Sensen C W, Doolittle W F, Brown J R
Department of Biology, University of Ottawa, Ontario, Canada.
J Bacteriol. 1997 Jul;179(13):4429-32. doi: 10.1128/jb.179.13.4429-4432.1997.
While sequencing the genome of the archaeon Sulfolobus solfataricus P2, we found an 8,313-bp sequence containing a cluster of nine histidine biosynthesis genes in an order different from that of any known his operon. Results of phylogenetic analysis of the coding regions in the putative operon give conflicting evolutionary histories for individual his genes.
在对嗜热栖热菌P2株的基因组进行测序时,我们发现了一个8313 bp的序列,其中包含一组九个组氨酸生物合成基因,其排列顺序与任何已知的组氨酸操纵子不同。对该假定操纵子编码区的系统发育分析结果显示,各个组氨酸基因有着相互矛盾的进化史。