Harris N L
Massachusetts General Hospital, Boston, USA.
Ann Oncol. 1997;8 Suppl 2:11-6.
The International Lymphoma Study Group has proposed a consensus classification for lymphoid neoplasms. Lymphoid neoplasms are defined as distinct biological entities, based on a combination of morphologic, immunophenotypic, genetic, and clinical features. Each distinct disease may have a range of histologic grade and clinical aggressiveness. Although many distinct diseases can now be recognized, three of them (follicular lymphoma, diffuse large B-cell lymphoma, and Hodgkin's disease) account for the majority of the cases seen in Europe and the USA. Recognition of distinct disease entities is essential in order to develop and test effective therapies.
国际淋巴瘤研究组已经提出了淋巴样肿瘤的共识分类。淋巴样肿瘤基于形态学、免疫表型、遗传学和临床特征的组合被定义为不同的生物学实体。每种不同的疾病可能有一系列的组织学分级和临床侵袭性。尽管现在可以识别出许多不同的疾病,但其中三种(滤泡性淋巴瘤、弥漫性大B细胞淋巴瘤和霍奇金病)占欧洲和美国所见病例的大多数。识别不同的疾病实体对于开发和测试有效的治疗方法至关重要。