Schwartz P J, Rosenthal N E, Turner E H, Drake C L, Liberty V, Wehr T A
National Institute of Mental Health, Clinical Psychobiology Branch, Bethesda, Maryland 20892-1390, USA.
Biol Psychiatry. 1997 Jul 15;42(2):122-31. doi: 10.1016/S0006-3223(96)00332-0.
Nocturnal core temperature during sleep is elevated during depression compared with remission in nonseasonally depressed patients. Similarly, nocturnal core temperature is higher during winter depression compared with remission induced by light treatment in seasonal affective disorder (SAD) patients. We investigated whether nocturnal core temperature in SAD patients naturally becomes lower in summer (during remission) compared with winter (during depression). Twenty-four-hour core temperature profiles were obtained in winter and summer in 22 SAD patients and 22 controls. The nocturnal core temperature minima were lower in summer compared with winter in SAD patients (p < .005), but not controls (p > .4). The seasonal changes in nocturnal core temperatures in SAD patients may reflect a unique physiological responsiveness of SAD patients to the change of seasons, and may be intimately related to the seasonal disturbances of mood and energy that are characteristic of SAD.
与非季节性抑郁症患者缓解期相比，抑郁症患者睡眠期间的夜间核心体温会升高。同样，与季节性情感障碍（SAD）患者经光照治疗诱导的缓解期相比，冬季抑郁症患者的夜间核心体温更高。我们研究了SAD患者的夜间核心体温在夏季（缓解期）是否自然会比冬季（抑郁期）更低。我们获取了22名SAD患者和22名对照者在冬季和夏季的24小时核心体温曲线。SAD患者夏季的夜间核心体温最低点低于冬季（p <.005），但对照者并非如此（p>.4）。SAD患者夜间核心体温的季节性变化可能反映了SAD患者对季节变化的独特生理反应，并且可能与SAD特有的情绪和精力的季节性紊乱密切相关。
