Celli P, Cervoni L, Salvati M, Cantore G
Department of Neurological Sciences, La Sapienza University of Rome, Italy.
J Neurooncol. 1997 Sep;34(2):153-6. doi: 10.1023/a:1005787422825.
The authors describe the unusual case of a patient requiring reoperation for ependymoma of the filum terminale after a symptom-free period of 42 years: treatment of the primary tumor consisted of macroscopically complete surgical excision and postoperative radiotherapy. This case brings to light some interesting observations: a late recurrence, as in the case reported here, appears to be rare especially if the tumor presents in adult age; the long preoperative clinical history (26 months) and the initial aspect of the tumor that infiltrated 2 caudal roots, removed together with the tumor, may have been factors correlated with the risk of recurrence: postoperative radiotherapy may have helped to delay clinical manifestation of the recurrence. Ependymomas of the filum terminale may clinically recur even after complete removal. The latest clinical recurrence described in the literature occurred after 26 years.
作者描述了一例罕见病例,一名患者在无症状期42年后因终丝室管膜瘤需要再次手术:原发肿瘤的治疗包括肉眼下完整手术切除及术后放疗。该病例揭示了一些有趣的观察结果:如此处报道的晚期复发似乎很少见,尤其是肿瘤发生于成年期;术前较长的临床病史(26个月)以及肿瘤最初侵犯2条尾神经根并与肿瘤一并切除,可能是与复发风险相关的因素:术后放疗可能有助于延迟复发的临床表现。终丝室管膜瘤即使在完全切除后仍可能出现临床复发。文献中描述的最新临床复发发生在26年后。