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芽生菌素皮肤试验的明显减弱;芽生菌病流行的随访

Apparent diminution of the blastomycin skin test; follow-up of an epidemic of blastomycosis.

作者信息

Sarosi G A, King R A

出版信息

Am Rev Respir Dis. 1977 Oct;116(4):785-8. doi: 10.1164/arrd.1977.116.4.785.

DOI:10.1164/arrd.1977.116.4.785
PMID:921056
Abstract

Eighteen persons involved in an epidemic of blastomycosis were followed for a period of 3 years. None of the symptomatic patients received antifungal therapy and all recovered spontaneously. During the period of follow-up observation all patients remained in excellent health, and none showed evidence of late exacerbation of the original illness. Two of the originally symptomatic patients continue to show stable pulmonary nodules on chest roentgenograms, whereas the previously abnormal chest roentgenograms in the other patients have become negative. Sixteen of these 18 patients showed a minimum of 5 mm of induration when tested with blastomycin skin test antigen. During the period of observation, the size of this induration tended to diminish.

摘要

对18例芽生菌病流行中的患者进行了为期3年的随访。所有有症状的患者均未接受抗真菌治疗,全部自行康复。在随访观察期间,所有患者健康状况良好,均无原发病迟发加重的迹象。最初有症状的2例患者胸部X线片上仍显示稳定的肺结节,而其他患者之前异常的胸部X线片已转为正常。这18例患者中有16例用芽生菌素皮肤试验抗原检测时硬结至少为5毫米。在观察期间,这种硬结的大小有缩小趋势。

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Apparent diminution of the blastomycin skin test; follow-up of an epidemic of blastomycosis.芽生菌素皮肤试验的明显减弱;芽生菌病流行的随访
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引用本文的文献

1
Blastomyces dermatitidis antigen-induced lymphocytes reactivity in human blastomycosis.皮炎芽生菌抗原诱导的人芽生菌病淋巴细胞反应性
Infect Immun. 1981 Aug;33(2):485-90. doi: 10.1128/iai.33.2.485-490.1981.
2
Immunohistopathological studies of blastomycosis: the use of labeled specific antigens in a hamster model of disease.芽生菌病的免疫组织病理学研究:在疾病的仓鼠模型中使用标记的特异性抗原。
Mycopathologia. 1984 Mar 15;85(1-2):17-20. doi: 10.1007/BF00436697.