伴放线放线杆菌在牙周病发病机制中的作用。
The role of Actinobacillus actinomycetemcomitans in the pathogenesis of periodontal disease.
作者信息
Meyer D H, Fives-Taylor P M
机构信息
Dept of Microbiology and Molecular Genetics, College of Medicine and College of Agricultural and Life Sciences, University of Vermont, Burlington 05405, USA.
出版信息
Trends Microbiol. 1997 Jun;5(6):224-8. doi: 10.1016/S0966-842X(97)01055-X.
PMID:9211642
Abstract
Periodontal disease consists of a constellation of complex bacterium-host cell interactions. One example of these oral pathogens, Actinobacillus actinomycetemcomitans, has an arsenal of putative virulence determinants that account for its potent periodontopathogenicity. Of these determinants, invasion of host cells and leukocytotoxicity have been studied extensively.
摘要
牙周病由一系列复杂的细菌与宿主细胞相互作用构成。这些口腔病原体中的一个例子，伴放线放线杆菌，拥有一系列假定的毒力决定因素，这些因素解释了它强大的牙周致病性。在这些决定因素中，宿主细胞侵袭和白细胞毒性已得到广泛研究。
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