Fishbein S L, Schwartz B
Arch Ophthalmol. 1977 Nov;95(11):1975-9. doi: 10.1001/archopht.1977.04450110069003.
The topography and extent of localized areas of hypofluorescence or absolute filling defects of the optic discs of glaucomatous patients correlated positively with the loss of visual field. Filling defects tended to cluster at the inferior and superior poles of the optic disc and were closer to the disc margin than to the center. The location of the defects corresponded with the expected site of visual field loss. There was a positive correlation between the percent area of the filling defects and the degree of visual field loss. These observations support the concept that fluorescein filling defects of the optic disc in glaucoma represent areas of ischemia that are highly correlated with loss of visual field.
青光眼患者视盘局部低荧光或绝对充盈缺损的形态及范围与视野缺损呈正相关。充盈缺损倾向于聚集在视盘的上下极，且更靠近视盘边缘而非中心。缺损的位置与预期的视野缺损部位相对应。充盈缺损面积百分比与视野缺损程度呈正相关。这些观察结果支持这样一种观点，即青光眼视盘的荧光素充盈缺损代表了与视野缺损高度相关的缺血区域。
