Eley B M
Periodontal Department, King's College School of Medicine & Dentistry, Denmark Hill, London.
Br Dent J. 1997 Jun 14;182(11):413-7. doi: 10.1038/sj.bdj.4809401.
This is the fifth article in a series of seven on the future of dental amalgam. This covers the studies of mercury distribution to the blood, body organs and the fetus and its excretion in the urine and faeces of humans and experimental animals. It firstly describes the clinical studies comparing the blood and urine mercury levels in patients with and without amalgam fillings and goes on to consider attempts which have been made to calculate tolerable mercury thresholds for the urine. It secondly describes the studies on the body distribution of mercury from amalgam restorations in experimental animals and human cadavers. It finally describes the studies of mercury distribution to the fetus during pregnancy and includes both studies of experimental animals and human clinical studies. The factors affecting the accuracy of these calculations and the relevance of these results is also extensively discussed.
这是关于牙科汞合金未来的七篇系列文章中的第五篇。本文涵盖了汞在血液、身体器官和胎儿中的分布研究，以及其在人类和实验动物尿液与粪便中的排泄情况。文章首先描述了比较有和没有汞合金填充物的患者血液和尿液中汞含量的临床研究，接着探讨了为计算尿液中汞的可耐受阈值所做的尝试。其次描述了在实验动物和人体尸体中关于汞合金修复体中汞的身体分布研究。最后描述了孕期汞在胎儿中的分布研究，包括实验动物研究和人类临床研究。同时还广泛讨论了影响这些计算准确性的因素以及这些结果的相关性。
