Prior P, Waterhouse J A
Br J Cancer. 1977 Sep;36(3):362-8. doi: 10.1038/bjc.1977.201.
In a series of patients drawn from the Birmingham Regional Cancer Registry (England) with tumours of the salivary glands, a significant excess of second primary tumours was observed. For females, the excess was found mainly in breast and bronchus and, for males, in prostate and skin. In a parallel series of female breast-cancer patients, the observed number of second primary tumours in salivary glands significantly exceeded expectation. These results support the reported association between salivary gland and breast cancer, and suggest that other hormone-dependent sites are also at risk.
在一系列来自伯明翰地区癌症登记处(英国)的涎腺肿瘤患者中,观察到第二原发性肿瘤显著过多。对于女性,这种过多主要见于乳腺和支气管;对于男性,则见于前列腺和皮肤。在一系列平行的女性乳腺癌患者中,涎腺中观察到的第二原发性肿瘤数量显著超过预期。这些结果支持了所报道的涎腺癌与乳腺癌之间的关联,并表明其他激素依赖部位也有风险。