Lean J S, Chignell A H
Br J Ophthalmol. 1977 Sep;61(9):593-4. doi: 10.1136/bjo.61.9.593.
Since the introduction of gentamicin (given both as a soaked sponge and as an injection below Tenon's capsule at the end of surgery) no case of early infection either with or without intraocular signs after operation for retinal detachment has occurred in a series of 206 cases comprising 243 operations. However, late infection many months after operation has appeared in 3 cases (1-5%), though this rate appears to have been favourably influenced by the administration of gentamicin. Local or systemic side effects from the administration of gentamicin have not been seen, and therefore the sub-Tenon injection in the quadrant where the sponge has been placed is strongly advocated in all cases of surgery for retinal detachment when such sponges are used.
自引入庆大霉素(手术结束时以浸湿的海绵形式及在眼球筋膜囊下注射的方式给药)以来,在包含243次手术的206例视网膜脱离手术病例系列中,术后无论有无眼内体征均未发生早期感染的情况。然而,术后数月出现了3例迟发性感染(1.5%),不过这一发生率似乎因庆大霉素的使用而受到了有利影响。未观察到庆大霉素给药引起的局部或全身副作用,因此,在所有使用此类海绵的视网膜脱离手术病例中,强烈主张在放置海绵的象限进行眼球筋膜下注射。