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民航飞行员和机组人员外周血淋巴细胞中电离辐射诱导的染色体畸变增加。

Increase of chromosomal aberrations induced by ionising radiation in peripheral blood lymphocytes of civil aviation pilots and crew members.

作者信息

Romano E, Ferrucci L, Nicolai F, Derme V, De Stefano G F

机构信息

Dipartimento di Biologia, Università degli Studi di Roma Tor Vergata, Rome, Italy.

出版信息

Mutat Res. 1997 Jun 9;377(1):89-93. doi: 10.1016/s0027-5107(97)00064-x.

DOI:10.1016/s0027-5107(97)00064-x
PMID:9219583
Abstract

This study inquires if there is an increase of chromosomal aberrations by ionising radiation of cosmic origin in civil pilots and flight-crew members. Totals of 37,208 exposed cells and 10,950 control cells, from 192 and 55 donors respectively, were scored averaging 200 observations per subject. The analysis showed the increase of dicentric and ring chromosomes in peripheral blood lymphocytes of the flight personnel. The difference of the total aberration frequencies between exposed and control was statistically significant.

摘要

本研究探讨民航飞行员和机组人员因宇宙起源的电离辐射导致染色体畸变是否增加。分别从192名和55名供体获取了总计37208个受照射细胞和10950个对照细胞,每位受试者平均进行200次观察评分。分析显示飞行人员外周血淋巴细胞中的双着丝粒染色体和环状染色体增加。受照射组与对照组的总畸变频率差异具有统计学意义。

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