掺入的脑苷脂对脂质体与HeLa细胞相互作用的影响。
Influence of incorporated cerebrosides on the interaction of liposomes with HeLa cells.
作者信息
Bussian R W, Wriston J C
出版信息
Biochim Biophys Acta. 1977 Dec 1;471(2):336. doi: 10.1016/0005-2736(77)90261-9.
PMID:921985
Abstract
The presence of synthetic N-palmitoyl dihydrolactocerebroside in preparations of neutral multilamellar liposomes enhances their fusion interaction with cultured HeLa cells some 5-7 fold. The effect appears to be carbohydrate-specific, and is probably not attributable to a change in the physical characteristics of the liposome bilayer due to the presence of the cerebroside.
摘要
中性多层脂质体制剂中合成的N-棕榈酰二氢乳糖脑苷脂的存在，使其与培养的HeLa细胞的融合相互作用增强了约5至7倍。这种效应似乎具有碳水化合物特异性，并且可能不是由于脑苷脂的存在导致脂质体双层物理特性的改变所致。
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