Brooks L J, DiFiore J M, Martin R J
Department of Pediatrics, Rainbow Babies and Childrens Hospital, Case Western Reserve University, Cleveland, Ohio, USA.
Pediatr Pulmonol. 1997 Jun;23(6):429-33. doi: 10.1002/(sici)1099-0496(199706)23:6<429::aid-ppul6>3.0.co;2-d.
Non-invasive techniques for monitoring ventilation in infants are widely used in short-term laboratory-studies but have not been evaluated in routine clinical settings. To determine whether respiratory inductance plethysmography (RIP) can provide reproducible measurements of tidal volume (VT) in premature infants over an extended period of time, we monitored respiration in eight healthy preterm infants over 4.9 +/- 1.0 hours (mean +/- SD). The algebraic sum (Sum) of rib cage (RC) and abdominal (AB) motion signals (obtained by RIP) was calculated and presented over the entire recording period as percent of an initial 5 minute calibration period. VT was simultaneously measured with a nasal mask pneumotachometer with infants in prone and supine positions during active and quiet sleep. Infants were studied in the morning (AM) and again in the afternoon (PM). Between these studies they were returned to the nursery wearing the RIP in a continuous record mode. For all patients there was a significant linear relationship between VT (in mL measured by pneumotachometer) and Sum (in % of calibration value, RIP). Neither the slope of the relationship (0.074 +/- 0.03 in AM vs. 0.071 +/- 0.02 in PM), nor its variability as measured by standard error of the estimate (SEE) (2.3 +/- 0.5 in AM vs. 2.5 +/- 0.8 in PM) changed significantly from AM to PM. The relationship between VT and Sum, as well as the variability of that relationship, was not altered by position, asynchrony of RC and AB, respiratory rate, or percent RC contribution to Sum. We conclude that RIP produces consistent measurements of respiratory effort over 5 hours in healthy preterm infants without need for recalibration and is not affected by routine care.
用于监测婴儿通气的非侵入性技术在短期实验室研究中被广泛使用，但尚未在常规临床环境中进行评估。为了确定呼吸感应体积描记法（RIP）能否在较长时间内为早产儿提供可重复的潮气量（VT）测量值，我们对8名健康早产儿进行了4.9±1.0小时（平均±标准差）的呼吸监测。计算胸廓（RC）和腹部（AB）运动信号（通过RIP获得）的代数和（Sum），并在整个记录期间以最初5分钟校准期的百分比形式呈现。在婴儿处于俯卧位和仰卧位的主动睡眠和安静睡眠期间，使用鼻罩式呼吸流速计同时测量VT。婴儿在上午（AM）和下午（PM）各进行一次研究。在这些研究之间，他们戴着RIP以连续记录模式返回育婴室。对于所有患者，VT（通过呼吸流速计测量，单位为mL）与Sum（以校准值的百分比表示，RIP）之间存在显著的线性关系。从上午到下午，该关系的斜率（上午为0.074±0.03，下午为0.071±0.02）及其通过估计标准误差（SEE）测量的变异性（上午为2.3±0.5，下午为2.5±0.8）均无显著变化。VT与Sum之间的关系以及该关系的变异性不受体位、RC和AB的不同步、呼吸频率或RC对Sum的贡献百分比的影响。我们得出结论，RIP在健康早产儿中可在长达5小时内产生一致的呼吸努力测量值，无需重新校准，且不受常规护理的影响。
