生物技术工程疫苗和诊断方法在伪狂犬病（奥耶斯基氏病）根除策略中的作用。

The role of biotechnologically engineered vaccines and diagnostics in pseudorabies (Aujeszky's disease) eradication strategies.

作者信息

Mengeling W L, Brockmeier S L, Lager K M, Vorwald A C

机构信息

Virology Swine Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA.

出版信息

Vet Microbiol. 1997 Apr;55(1-4):49-60. doi: 10.1016/s0378-1135(96)01306-5.

DOI:10.1016/s0378-1135(96)01306-5

PMID:9220596

Abstract

Modern-day biotechnology has an almost unlimited number of possibilities for reducing the impact of hereditary and infectious diseases. To date one of its most visible and rewarding applications for veterinary medicine has been in the genetic engineering of vaccines and diagnostics to assist in the eventual eradication of pseudorabies (PR, Aujeszky's disease). In the following review we summarize some of the most pertinent issues relative to PR eradication and point out the present and potential role of biotechnology in achieving our goal.

摘要

现代生物技术在减少遗传性和传染性疾病影响方面有着几乎无限的可能性。迄今为止，其在兽医学中最显著且有价值的应用之一是在疫苗和诊断的基因工程方面，以协助最终根除伪狂犬病（PR，奥耶斯基氏病）。在以下综述中，我们总结了与根除伪狂犬病相关的一些最相关问题，并指出生物技术在实现我们目标方面的当前和潜在作用。