Stegeman A, De Jong M C, Van der Heijden H M, Elbers A R, Kimman T G
Animal Health Service, Boxtel, The Netherlands.
Vet Microbiol. 1997 Apr;55(1-4):107-11. doi: 10.1016/s0378-1135(96)01312-0.
Receiver operating characteristic (ROC) curves assess the quality of tests over the entire range of test signals. We compared the ability of an ELISA to detect antibodies to Aujeszky's disease (pseudorabies) virus gE in colostrum (test A) and in a single droplet of whole blood (test B) with the results obtained in serum (gold standard) in the target population by constructing and analyzing such curves. The area under the ROC curve, which is a quantitative measure of test performance, proved to be significantly (p < 0.01) smaller in test A than in test B or the gold standard. No significant differences in the area under the ROC curve were observed between test B and the gold standard.
受试者工作特征（ROC）曲线可在整个测试信号范围内评估检测的质量。我们通过构建和分析此类曲线，比较了酶联免疫吸附测定（ELISA）检测初乳（检测A）和单滴全血（检测B）中伪狂犬病病毒gE抗体的能力与目标人群血清检测结果（金标准）。ROC曲线下面积是检测性能的定量指标，结果表明检测A的ROC曲线下面积显著（p < 0.01）小于检测B或金标准。检测B与金标准之间的ROC曲线下面积未观察到显著差异。
