Nagaya H
Ann Allergy. 1979 Nov;43(5):267-70.
Although the total serum IgE level is generally higher in atopic than in non-atopic individuals, high total serum IgE levels and atopic diseases are not invariably associated. In 42 atopic patients with the total serum IgE levels less than 100 U/ml, 27% of RAST against 14 allergens were positive whereas in 45 atopic patients with the total serum IgE levels greater than 500 U/ml, 57% of RAST against 14 allergens were positive. The mean RAST values against four grass antigens expressed as a percentage of antigen-disc bound radioactivities were significantly lower in the group with the lower total serum IgE levels. Low or normal total serum IgE levels are likely to be found in atopic patients who are allergic to a relatively few grass antigens.
虽然特应性个体的血清总IgE水平通常高于非特应性个体，但血清总IgE水平升高与特应性疾病并非总是相关。在42例血清总IgE水平低于100 U/ml的特应性患者中，针对14种变应原的RAST检测有27%呈阳性，而在45例血清总IgE水平高于500 U/ml的特应性患者中，针对14种变应原的RAST检测有57%呈阳性。血清总IgE水平较低组中，针对四种草类抗原的平均RAST值（以抗原盘结合放射性的百分比表示）显著较低。对相对较少草类抗原过敏的特应性患者可能血清总IgE水平较低或正常。
