Sigal E R, Koriazova L K, Kovalevskaia G I, Pozdniakova T A, Kandyba E I, Kuznetsov V A, Vasilov R G
Klin Lab Diagn. 1997 Apr(4):21-4.
An enzyme immunoassay kit based on monoclonal antibodies (Mab) has been developed for measuring thyroid-stimulating hormone in human serum and plasma. Laboratory trials demonstrated its high sensitivity (3.1 microIU/ml), specificity, reliability, and accuracy. The analysis is simple and rapid (2.5 h), which is convenient for clinical use. The kit permits differentiation between normal subjects and patients with primary hypo- or hyperthyroidism and helps monitor the treatment efficacy. Comparison with the Amerlite TSH-60 kit, carried out on 357 sera, showed a high correlation coefficient (0.96) between the two kits.
已开发出一种基于单克隆抗体（Mab）的酶免疫分析试剂盒，用于测定人血清和血浆中的促甲状腺激素。实验室试验证明了其高灵敏度（3.1微国际单位/毫升）、特异性、可靠性和准确性。该分析简单快速（2.5小时），便于临床使用。该试剂盒可区分正常受试者与原发性甲状腺功能减退或亢进患者，并有助于监测治疗效果。对357份血清进行的与Amerlite TSH - 60试剂盒的比较显示，两种试剂盒之间的相关系数很高（0.96）。
