J Atheroscler Thromb. 1996;2(2):122-32. doi: 10.5551/jat1994.2.122.
To determine the recent serum lipid levels in the general Japanese population and trends in their changes over the past 30 years, a nationwide survey of serum lipid levels was conducted in 39 institutes from various districts around Japan. The total number of subjects were 34,815, consisting of 20,279 men and 14,536 women aged 4 through 99 years. All the serum samples were collected and analyzed within one week at the Special Research Laboratory (Tokyo, Japan). In males, the mean serum cholesterol level showed a gradually increase from 170 mg/dl in the 0- to 9-year-old age group to 198 mg/dl in the 50- to 59-year-old age group. There was a slight decrease after age 60 years. In females, the mean cholesterol level gradually rose with age from 173 mg/dl in the 0- to 9-year-old age group to 210 mg/dl in the 60- to 69-year-old age group, and fell to 207 mg/dl after 80 years of age. The mean HDL-cholesterol level in men gradually decreased with age from 60 mg/dl in the 0- to 9-year-old age group to 51 mg/dl in the 30- to 39-year-old age group, remained at this level up to 69 years of age, and then increased to 54 mg/dl for the above 80 years old group. The mean HDL-cholesterol level in women increased from 57 mg/dl in the 0- to 9-year-old age group to 62 mg/dl for the 20- to 29-year-old age group: then gradually decreased with age to 54 mg/dl in the 60- to 79-year-old age group. The mean LDL-cholesterol level in men gradually increased with age from 98 mg/dl in the 0- to 19-year-old age group to 122 mg/dl at 70-79 years of age. The mean LDL-cholesterol level in women was low at 101-103 mg/dl up to 29 years of age, then it increased with age to 135 mg/dl in the 60- to 69-year-old age group. The serum cholesterol levels in 1970 and 1980 were higher than that in 1960, but in 1990 values similar to those in 1960 were observed in both men and women. The present results will become the standard serum lipid level data for the Japanese people, and succeeding 10-year surveys will clarify the trends of lipid levels in this country.
为了确定日本普通人群近期的血脂水平及其在过去30年中的变化趋势，在日本各地的39个机构进行了一项全国性的血脂水平调查。受试者总数为34,815人，包括20,279名男性和14,536名4至99岁的女性。所有血清样本均在日本东京的特殊研究实验室在一周内收集并分析。在男性中，平均血清胆固醇水平从0至9岁年龄组的170mg/dl逐渐升高至50至59岁年龄组的198mg/dl。60岁以后略有下降。在女性中，平均胆固醇水平随年龄逐渐升高，从0至9岁年龄组的173mg/dl升至60至69岁年龄组的210mg/dl，并在80岁以后降至207mg/dl。男性的平均高密度脂蛋白胆固醇水平随年龄逐渐降低，从0至9岁年龄组的60mg/dl降至30至39岁年龄组的51mg/dl，在69岁之前保持在该水平，然后在80岁以上组升至54mg/dl。女性的平均高密度脂蛋白胆固醇水平从0至9岁年龄组的57mg/dl升至20至29岁年龄组的62mg/dl：然后随年龄逐渐降低至60至79岁年龄组的54mg/dl。男性的平均低密度脂蛋白胆固醇水平从0至19岁年龄组的98mg/dl随年龄逐渐升高至70至79岁时的122mg/dl。女性的平均低密度脂蛋白胆固醇水平在29岁之前较低，为101-103mg/dl，然后随年龄增加至60至69岁年龄组的135mg/dl。1970年和1980年的血清胆固醇水平高于1960年，但在1990年，男性和女性的数值与1960年相似。目前的结果将成为日本人的标准血脂水平数据，后续的10年调查将阐明该国血脂水平的趋势。
