Sekiya M, Sekigawa I, Hishikawa T, Iida N, Hashimoto H, Hirose S
Department of Respiratory Medicine, Juntendo Izunagaoka Hospital, Tokyo, Japan.
Scand J Rheumatol. 1997;26(3):215-7. doi: 10.3109/03009749709065684.
Recent reports have indicated that nodular regenerative hyperplasia (NRH) associated with systemic lupus erythematosus (SLE) is related to anticardiolipin antibodies (aCL) and/or lupus anticoagulant (LA). We describe a patient with SLE complicated by NRH, who did not show neither aCL nor LA activity. This case suggests that the pathogenesis of NRH in patients with autoimmune diseases is heterogeneous and not confined to aCL and LA.
近期报告表明，与系统性红斑狼疮（SLE）相关的结节性再生性增生（NRH）与抗心磷脂抗体（aCL）和/或狼疮抗凝物（LA）有关。我们描述了一名患有SLE并伴有NRH的患者，该患者既未表现出aCL活性，也未表现出LA活性。该病例表明，自身免疫性疾病患者中NRH的发病机制是异质性的，并不局限于aCL和LA。
