Pasman W J, Westerterp-Plantenga M S, Muls E, Vansant G, van Ree J, Saris W H
Department of Human Biology, Maastricht University, Netherlands.
Int J Obes Relat Metab Disord. 1997 Jul;21(7):548-55. doi: 10.1038/sj.ijo.0800439.
To investigate whether fibre supplementation is effective in weight-reduced subjects for maintenance of weight-loss in the long-term.
Longitudinal, randomly assigned intervention study with supplementation of 20 g of water soluble fibre (guar gum) daily for 14 months after an energy-restricted period of two months (VLCD).
Thirty-one female, obese subjects (age: 41.4 +/- 7.4 y: BMI 33.2 +/- 3.7 kg/m-2); 20 subjects were supplemented with fibre and 11 subjects served as the control group.
Body weight (BW), blood lipids and blood pressure, anthropometry, and eating behaviour were measured before the VLCD (0), after VLCD (2), and at 4, 10, and 16 months.
The fibre group with at least 80% compliance (group A) and the control group showed the same weight regain response after VLCD. The fibre consuming group with 50-80% compliance (group B) differed with respect to relapse. The rate and amount of BW regain was significantly higher for group B. After 14 months group B had returned to baseline levels, whereas group A and the control group showed a tendency to a lower BW than at baseline (P = 0.09). No effect of fibre supplementation was found on blood lipids, blood pressure and energy intake. Eating behaviour characteristics changed during the intervention and might explain differences in weight maintenance.
No effect of 14 months fibre supplementation was found on weight maintenance in weight-reduced subjects. Guar gum intake did not result in reduction of blood pressure or cholesterol, or in suppression of energy intake.
研究补充纤维对体重减轻的受试者长期维持体重减轻是否有效。
纵向、随机分配的干预研究，在两个月的能量限制期（极低热量饮食）后，每天补充20克水溶性纤维（瓜尔胶），持续14个月。
31名肥胖女性受试者（年龄：41.4±7.4岁；体重指数33.2±3.7kg/m²）；20名受试者补充纤维，11名受试者作为对照组。
在极低热量饮食前（0个月）、极低热量饮食后（2个月）以及4、10和16个月时测量体重（BW）、血脂、血压、人体测量指标和饮食行为。
依从性至少为80%的纤维组（A组）和对照组在极低热量饮食后体重恢复情况相同。依从性为50 - 80%的纤维摄入组（B组）在复发方面存在差异。B组体重恢复的速率和量显著更高。14个月后，B组已恢复到基线水平，而A组和对照组的体重有低于基线的趋势（P = 0.09）。未发现补充纤维对血脂、血压和能量摄入有影响。干预期间饮食行为特征发生了变化，这可能解释了体重维持方面的差异。
未发现14个月的纤维补充对体重减轻的受试者维持体重有影响。摄入瓜尔胶未导致血压或胆固醇降低，也未抑制能量摄入。
