Sidhu R S, Sharma R K, Kachoria S, Curtis C, Agarwal A
Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA.
J Assist Reprod Genet. 1997 Jul;14(6):354-60. doi: 10.1007/BF02765841.
Recruiting donors to a sperm bank program is difficult and slow because of high dropout rates and high rejection rates. The profile of successful and unsuccessful donors was determined at our sperm bank.
A total of 199 men was screened from 1986 to 1994 in the anonymous sperm bank donor programs; 174 (87%) men dropped out or did not meet minimum guidelines. The study included 25 accepted donors and 20 rejected men (of 52 rejected donors, only 20 donors who came for two consecutive semen analyses were selected). Sperm quality variables and demographic data were compared between the groups.
Accepted donors had significantly better semen quality in motility, velocity, linearity, and ALH than did rejected donors (P < 0.01). More rejected donors than accepted donors were single (P < 0.01). A higher percentage of accepted donors consumed caffeine (P < 0.001), and they were more likely to have college degrees (P < 0.03).
These results indicate that loss of interest and poor semen quality were the major reasons for rejection of donors in our anonymous donor sperm bank program.
由于高退出率和高拒绝率，为精子库项目招募捐赠者困难且进展缓慢。我们对精子库中成功和不成功的捐赠者特征进行了研究。
1986年至1994年期间，共有199名男性在匿名精子库捐赠者项目中接受筛选；174名（87%）男性退出或未达到最低标准。该研究纳入了25名被接受的捐赠者和20名被拒绝的男性（在52名被拒绝的捐赠者中，仅选择了20名连续前来进行两次精液分析的捐赠者）。对两组之间的精子质量变量和人口统计学数据进行了比较。
被接受的捐赠者在活力、速度、直线性和平均路径速度方面的精液质量明显优于被拒绝的捐赠者（P < 0.01）。单身的被拒绝捐赠者比被接受的捐赠者更多（P < 0.01）。被接受的捐赠者中饮用咖啡因的比例更高（P < 0.001），而且他们更有可能拥有大学学位（P < 0.03）。
这些结果表明，兴趣丧失和精液质量差是我们匿名捐赠者精子库项目中捐赠者被拒绝的主要原因。
