Lyles A, Luce B R, Rentz A M
Johns Hopkins University, Department of Health Policy and Management, Baltimore, MD 21205, USA.
Soc Sci Med. 1997 Aug;45(4):511-21. doi: 10.1016/s0277-9536(96)00392-9.
A telephone survey of a representative national sample of 51 large managed care organizations in the U.S. (> 50,000 enrollees) was undertaken (1) to understand the role of socioeconomic assessments on drug adoption decisions; (2) to determine the sources of these assessments and the reliance of managed care pharmacy on each; and (3) to determine the resources for internally versus externally performed drug assessments. Socioeconomic assessments (clinical effectiveness, safety, cost of treatment, cost-effectiveness, and quality of life) are often tied to formulary decisions. Plans differ in their use of externally available socioeconomic assessments and in their ratings of the importance to decision making of drug assessments from the various sources. Those using a specific source of drug assessment information rated them in the following order of importance: PBM assessments, other HMOs, peer reviewed literature, evaluations performed by industry, articles in non-peer reviewed publications and, lastly, government reports. Timeliness and comprehensiveness are important components of the overall utility of information. A high percentage of plans reported using some of the various types of assessments, with clinical effectiveness most common, and cost-effectiveness second. The percentage of new drugs that undergo assessments in each of the plans covers a broad range, with 57% of the plans evaluating at least half of all new drugs. All but one surveyed managed care plan reported having either implemented or plans to implement a disease management program. Eighty percent of those surveyed are more concerned about drug assessments than in the past and 88% anticipate greater future use. Although 38 plans (75%) have a person in the organization responsible for drug assessments, this is the primary job in only 14 plans (37%). With greater reliance on drug assessments in the future, there are substantial opportunities for integrating drug assessments, formularies and disease management programs.
对美国51家大型管理式医疗组织(参保人数超过5万)的具有代表性的全国样本进行了电话调查,目的如下:(1)了解社会经济评估在药物采用决策中的作用;(2)确定这些评估的来源以及管理式医疗药房对每种来源的依赖程度;(3)确定内部与外部进行药物评估的资源。社会经济评估(临床疗效、安全性、治疗成本、成本效益和生活质量)通常与处方集决策相关。各计划在使用外部可得的社会经济评估以及对来自不同来源的药物评估在决策重要性方面的评级存在差异。使用特定药物评估信息来源的那些计划按以下重要性顺序对其进行评级:药品福利管理机构(PBM)评估、其他健康维护组织(HMO)、同行评审文献、行业进行的评估、非同行评审出版物中的文章,最后是政府报告。及时性和全面性是信息整体效用的重要组成部分。很大比例的计划报告使用了某些类型的评估,其中临床疗效最常见,成本效益其次。每个计划中接受评估的新药百分比范围很广,57%的计划评估了至少一半的新药。除一家受调查的管理式医疗计划外,所有计划均报告已实施或计划实施疾病管理计划。80%的受调查者比过去更关注药物评估,88%预计未来会更多地使用。尽管38个计划(75%)在组织中有专人负责药物评估,但这仅是14个计划(37%)中的主要工作。随着未来对药物评估的更大依赖,整合药物评估、处方集和疾病管理计划存在大量机会。