Liu L L, Clemens C J, Shay D K, Davis R L, Novack A H
Department of Pediatrics, University of Washington, Seattle, USA.
JAMA. 1997;278(4):293-8.
While early discharge of newborns following routine vaginal delivery has become common practice, its safety has not been firmly established.
To assess the risk for rehospitalization following newborn early discharge.
Population-based, case-control study.
Washington State linked birth certificate and hospital discharge abstracts covering 310578 live births from 1991 through 1994.
Case patients were 2029 newborns rehospitalized in the first month of life. Control subjects were 8657 randomly selected newborns not rehospitalized and frequency matched to case patients on year of birth. Cesarean deliveries, multiple births, and births at less than 36 weeks' gestation were not included.
Stratified analyses and logistic regression were performed to assess the risk for rehospitalization within a month of birth after early discharge (<30 hours after birth) compared with later discharge (30-78 hours after birth).
Seventeen percent of newborns were discharged early. Newborns discharged early were more likely to be rehospitalized within 7 days (odds ratio [OR], 1.28; 95% confidence interval [CI], 1.11-1.47), 14 days (OR, 1.16; 95% CI, 1.03-1.32), and 28 days (OR, 1.12; 95% CI, 1.00-1.25) of discharge than newborns sent home later. Subgroups at increased risk for rehospitalization following early discharge included newborns born to primigravidas (OR,1.25; 95% CI, 1.07-1.45), mothers younger than 18 years (OR, 1.22; 95% CI, 0.79-1.91), and mothers with premature rupture of membranes (OR, 1.41; 95% CI, 0.85-2.36). Early discharge was also associated with an increased risk of readmission for jaundice, dehydration, and sepsis.
Newborns discharged home early (<30 hours after birth) are at increased risk for rehospitalization during the first month of life.
虽然常规阴道分娩后新生儿早期出院已成为常见做法,但其安全性尚未得到确证。
评估新生儿早期出院后再次入院的风险。
基于人群的病例对照研究。
华盛顿州,关联了1991年至1994年310578例活产的出生证明和医院出院摘要。
病例组为2029例在出生后第一个月再次入院的新生儿。对照组为8657例随机选取的未再次入院的新生儿,按出生年份与病例组进行频数匹配。剖宫产、多胎妊娠及孕周小于36周的分娩不包括在内。
进行分层分析和逻辑回归,以评估早期出院(出生后<30小时)与较晚出院(出生后30 - 78小时)相比,出生后一个月内再次入院的风险。
17%的新生儿早期出院。早期出院的新生儿在出院后7天(比值比[OR],1.28;95%置信区间[CI],1.11 - 1.47)、14天(OR,1.16;95% CI,1.03 - 1.32)和28天(OR,1.12;95% CI,1.00 - 1.25)内再次入院的可能性高于较晚出院的新生儿。早期出院后再次入院风险增加的亚组包括初产妇所生新生儿(OR,1.25;95% CI,1.07 - 1.45)、年龄小于18岁的母亲所生新生儿(OR,1.22;95% CI,0.79 - 1.91)以及胎膜早破的母亲所生新生儿(OR,1.41;95% CI,0.85 - 2.36)。早期出院还与因黄疸、脱水和败血症再次入院的风险增加有关。
早期出院(出生后<30小时)的新生儿在出生后第一个月内再次入院的风险增加。