Edmonson M B, Stoddard J J, Owens L M
Department of Pediatrics, Center for Health Sciences, University of Wisconsin-Madison, 53792-4116, USA.
JAMA. 1997;278(4):299-303.
Increasingly short postpartum hospital stays in the United States precipitated a policy debate that culminated in passage of the Newborns' and Mothers' Health Protection Act of 1996. The debate occurred without population-based evidence for adverse health effects in newborns who are discharged early.
To determine whether early postpartum hospital discharge of normal newborns increases their risk for hospital readmission with feeding-related problems.
Nested case-control analysis of 1991 to 1994 Wisconsin birth certificate and hospital discharge data.
A total of 210 readmitted case patients and 630 control subjects selected from a cohort of 120 290 normal newborns who weighed at least 2500 g, were delivered vaginally of mothers with uncomplicated medical and obstetrical histories, and were discharged from the hospital either early (day of life 1 or 2) or conventionally (day 3).
Readmission at age 4 to 28 days with discharge diagnoses indicating a primary feeding problem, secondary dehydration, or inadequate weight gain.
Early discharges increased 3-fold (reaching 521/1000 discharges) during the study period, but feeding-related readmissions (1.7/1000) remained stable. Most readmitted newborns (53.8%) were 4 to 7 days old, many (34.3%) had concurrent dehydration and jaundice, and 29% were admitted through emergency departments. Readmitted newborns were significantly (P<.05) more likely to have been breast-fed, firstborn, or preterm or to have mothers who were poorly educated (<12th grade), unmarried, or receiving Medicaid. Readmission was not associated with early discharge (adjusted odds ratio, 1.05; 95% confidence interval, 0.71-1.53).
Although several neonatal and maternal factors increase the risk that a normal newborn will be rehospitalized with a feeding-related problem, early discharge following an uncomplicated postpartum hospital stay appears to have little or no independent effect on this risk.
美国产后住院时间日益缩短引发了一场政策辩论,最终促成了1996年《新生儿与母亲健康保护法》的通过。这场辩论进行时,并无基于人群的证据表明早出院的新生儿存在健康不良影响。
确定正常新生儿产后早期出院是否会增加其因喂养相关问题再次入院的风险。
对1991年至1994年威斯康星州出生证明和医院出院数据进行巢式病例对照分析。
从120290名正常新生儿队列中选取了210名再次入院的病例患者和630名对照对象,这些新生儿体重至少2500克,通过阴道分娩,母亲的内科和产科病史无并发症,且要么早期(出生后第1天或第2天)出院,要么常规(第3天)出院。
4至28日龄时再次入院,出院诊断表明存在主要喂养问题、继发性脱水或体重增加不足。
在研究期间,早期出院率增加了3倍(达到每1000例出院中有521例),但与喂养相关的再次入院率(每1000例中有1.7例)保持稳定。大多数再次入院的新生儿(53.8%)为4至7日龄,许多(34.3%)同时患有脱水和黄疸,29%是通过急诊科入院的。再次入院的新生儿更有可能是母乳喂养、头胎、早产,或者母亲受教育程度低(低于12年级)、未婚或接受医疗补助(P<0.05)。再次入院与早期出院无关(调整后的优势比为1.05;95%置信区间为0.71 - 1.53)。
尽管一些新生儿和母亲因素会增加正常新生儿因喂养相关问题再次住院的风险,但产后住院情况无并发症后早期出院似乎对此风险几乎没有或没有独立影响。