Jarskär R
Cell Tissue Res. 1977 Oct 21;184(1):121-32. doi: 10.1007/BF00220532.
The development of the nerve supply of the pituitary pars intermedia (PI) of C3H mice was studied by electron microscopy. Nerve fibres and terminal structures, most probably adrenergic, first appear in the newborn. The adult innervation pattern is achieved by the end of the first postnatal week. In the adult animal two types of nerve terminals were distinguished; type A (peptidergic or neurosecretory) and type B (adrenergic). The peptidergic fibres were scarce and exhibited no synapse-like contacts. It is suggested that they are of secondary importance in a direct nervous hypothalamic control of PI function. Type B terminals were found throughout the PI. They formed synapse-like contacts with the glandular cells, indicating that the primary innervation is exerted by adrenergic neurons. An autonomous differentiation of the glandular cells and in the adult a combined direct nervous and neurohumoral control of PI function is suggested.
通过电子显微镜研究了C3H小鼠垂体中间部（PI）神经供应的发育情况。神经纤维和终末结构，很可能是肾上腺素能的，最早出现在新生小鼠中。出生后第一周结束时形成成年期的神经支配模式。在成年动物中，区分出两种类型的神经终末；A型（肽能或神经分泌型）和B型（肾上腺素能型）。肽能纤维稀少，未表现出突触样联系。提示它们在垂体中间部功能的直接下丘脑神经控制中具有次要作用。B型终末见于整个垂体中间部。它们与腺细胞形成突触样联系，表明主要的神经支配由肾上腺素能神经元施加。提示腺细胞存在自主分化，且在成年期垂体中间部功能受神经和神经体液的联合直接控制。
