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新生儿重症监护病房和医疗重症监护病房的资源分配。生命两端的流行病学与资源配给。

Resource allocation in neonatal and medical ICUs. Epidemiology and rationing at the extremes of life.

作者信息

Lantos J D, Mokalla M, Meadow W

机构信息

Department of Pediatrics, University of Chicago Pritzker School of Medicine, Illinois, USA.

出版信息

Am J Respir Crit Care Med. 1997 Jul;156(1):185-9. doi: 10.1164/ajrccm.156.1.9510103.

DOI:10.1164/ajrccm.156.1.9510103
PMID:9230745
Abstract

This study compared resource allocation to patients who eventually die in neonatal ICUs (NICUs) and adult medical ICUs (MICUs). It was performed via retrospective, chart review study at ICUs at the University of Chicago-an inner city, tertiary care, academic medical center. All patients were admitted to the neonatal, general medical, or coronary ICU during 1 calendar yr. Overall mortality in the NICU (66/827; 7.9%) was significantly lower than in the adult ICUs (219/1320; 16.5%) (p < 0.001). However, mortality for the smallest newborns (< 751 g; 51% mortality) was higher than for the oldest adults (> 54 yr; 30% mortality) (p = 0.05). Fifty-six percent (37/66) of all neonates who died in the NICU did so within the first 48 hr of life. In contrast, nearly two-thirds (134/219) of adult ICU deaths occurred after 48 hours in the ICU (p < 0.02). The percentage of ICU bed-days devoted to nonsurviving adults (28.8%) was significantly larger than the percentage of NICU bed-days devoted to nonsurviving babies (7.8%). Even among babies at greatest risk to die (birth weight < 751 g), the percentage of NICU bed-days allocated to nonsurviving infants was less than 20%. In contrast, for the oldest ICU patients (> 84 yr) this value exceeded 50%, for ICU patients > 84 yr old who required mechanical ventilation, the percentage of ICU bed-days allocated to nonsurvivors approached 90%. Care for the elderly in MICUs involves a far greater proportional expenditure of money toward those who will not survive than does care for newborns in NICUs. To the extent that allocation decisions are driven by concerns about distributive justice and the efficient use of scarce resources, it would be more justifiable to ration intensive care for the very old than the very young.

摘要

本研究比较了最终在新生儿重症监护病房(NICU)和成人医学重症监护病房(MICU)死亡的患者的资源分配情况。该研究通过对芝加哥大学(一所市中心的三级医疗学术医学中心)重症监护病房进行回顾性病历审查研究来开展。所有患者在1个日历年期间被收治入新生儿、普通内科或冠心病重症监护病房。NICU的总体死亡率(66/827;7.9%)显著低于成人重症监护病房(219/1320;16.5%)(p<0.001)。然而,最小的新生儿(<751克;死亡率51%)的死亡率高于年龄最大的成年人(>54岁;死亡率30%)(p = 0.05)。在NICU死亡的所有新生儿中有56%(37/66)在出生后的头48小时内死亡。相比之下,成人重症监护病房近三分之二(134/219)的死亡发生在入住重症监护病房48小时之后(p<0.02)。用于救治未能存活的成年人的重症监护病房床日百分比(28.8%)显著高于用于救治未能存活的婴儿的NICU床日百分比(7.8%)。即使在死亡风险最高的婴儿(出生体重<751克)中,分配给未能存活婴儿的NICU床日百分比也不到20%。相比之下,对于年龄最大的重症监护病房患者(>84岁),这一数值超过了50%,对于需要机械通气的>84岁的重症监护病房患者,分配给未能存活者的重症监护病房床日百分比接近90%。与NICU中对新生儿的护理相比,MICU中对老年人的护理在那些无法存活的患者身上所涉及的资金支出比例要大得多。就分配决策受分配正义和稀缺资源有效利用的考量驱动而言,对老年人实施重症监护的资源配给比对非常年幼者更具合理性。

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