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受体在哺乳动物背角和初级传入神经元中的定位。

Receptor localization in the mammalian dorsal horn and primary afferent neurons.

作者信息

Coggeshall R E, Carlton S M

机构信息

Department of Anatomy and Neurosciences, University of Texas Medical Branch, Galveston 77555-1069, USA.

出版信息

Brain Res Brain Res Rev. 1997 Jun;24(1):28-66. doi: 10.1016/s0165-0173(97)00010-6.

DOI:10.1016/s0165-0173(97)00010-6
PMID:9233541
Abstract

The dorsal horn of the spinal cord is a primary receiving area for somatosensory input and contains high concentrations of a large variety of receptors. These receptors tend to congregate in lamina II, which is a major receiving center for fine, presumably nociceptive, somatosensory input. There are rapid reorganizations of many of these receptors in response to various stimuli or pathological situations. These receptor localizations in the normal and their changes after various pertubations modify present concepts about the wiring diagram of the nervous system. Accordingly, the present work reviews the receptor localizations and relates them to classic organizational patterns in the mammalian dorsal horn.

摘要

脊髓背角是躯体感觉输入的主要接收区域,含有高浓度的多种受体。这些受体倾向于聚集在板层II,而板层II是精细的、推测为伤害性的躯体感觉输入的主要接收中心。许多这些受体在各种刺激或病理情况下会迅速重新组织。这些受体在正常情况下的定位及其在各种扰动后的变化改变了目前关于神经系统接线图的概念。因此,本研究综述了受体的定位,并将它们与哺乳动物背角的经典组织模式联系起来。

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