Tóth T, Papp C, Tóth-Pál E, Nagy B, Papp Z
Semmelweis Orvostudományi Egyetem, I. sz. Szülészeti és Nögyógyászati Klinika, Budapest.
Orv Hetil. 1997 May 11;138(19):1203-5.
It is reported on a prenatal determination of fetal RhD blood group from blood of a sensitized RhD-positive mother at 11th week gestation. The result was confirmed by a subsequent amplification of fetal DNA obtained by chorionic villus biopsy. It is supposed that in sensitized pregnancies the high number of fetal RhD-positive red blood cells in maternal blood is enough to be detectable by polymerase chain reaction.
据报道，在妊娠第11周时，从一位致敏的RhD阳性母亲的血液中对胎儿RhD血型进行了产前测定。随后通过绒毛取样获得的胎儿DNA扩增证实了该结果。据推测，在致敏妊娠中，母血中大量的胎儿RhD阳性红细胞足以通过聚合酶链反应检测到。
