通过喹吖因荧光揭示的关于胆碱能激动剂与电鳐膜结合型乙酰胆碱受体相互作用的快速动力学研究。 - Suppr

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超能文献

Fast kinetic studies on the interaction of cholinergic agonists with the membrane-bound acetylcholine receptor from Torpedo marmorata as revealed by quinacrine fluorescence.

作者信息

Grünhagen H H, Iwatsubo M, Changeux J P

出版信息

Eur J Biochem. 1977 Oct 17;80(1):225-42. doi: 10.1111/j.1432-1033.1977.tb11875.x.

DOI:10.1111/j.1432-1033.1977.tb11875.x

PMID:923575

Abstract

摘要

相似文献

Fast kinetic studies on the interaction of cholinergic agonists with the membrane-bound acetylcholine receptor from Torpedo marmorata as revealed by quinacrine fluorescence.通过喹吖因荧光揭示的关于胆碱能激动剂与电鳐膜结合型乙酰胆碱受体相互作用的快速动力学研究。

Eur J Biochem. 1977 Oct 17;80(1):225-42. doi: 10.1111/j.1432-1033.1977.tb11875.x.

[Rapid changes in the intensity of fluorescence observed in the presence of cholinergic agonists with Torpedo marmorata membrane fragments rich in cholinergic receptors and labelled with quinacrine].[在富含胆碱能受体并用喹吖因标记的电鳐膜片段存在下，胆碱能激动剂存在时观察到的荧光强度的快速变化]

C R Acad Hebd Seances Acad Sci D. 1976 Oct 18;283(9):1105-8.

[Structural transitions of the Torpedo cholinergic receptor in its membrane state as demonstrated by a fluorescent local anesthetic: quinacrine].

C R Acad Hebd Seances Acad Sci D. 1975 Oct 6;281(14):1047-50.

Interaction of a fluorescent ligand with membrane-bound cholinergic receptor from Torpedo marmorata.

Biochemistry. 1973 Nov 20;12(24):4855-64. doi: 10.1021/bi00748a008.

Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. IV. Quinacrine: a fluorescent probe for the conformational transitions of the cholinergic receptor protein in its membrane-bound state.

J Mol Biol. 1976 Sep 25;106(3):497-516. doi: 10.1016/0022-2836(76)90249-7.

Effects of agonists and antagonists on the reactivity of the binding site disulfide in acetylcholine receptor from Torpedo californica.激动剂和拮抗剂对加州电鳐乙酰胆碱受体结合位点二硫键反应性的影响。

Biochemistry. 1980 Aug 19;19(17):3924-32. doi: 10.1021/bi00558a006.

Cholinergic synaptic vesicles isolated from Torpedo marmorata: demonstration of acetylcholine and choline uptake in an in vitro system.从电鳐分离出的胆碱能突触小泡：体外系统中乙酰胆碱和胆碱摄取的证明。

Neuroscience. 1980;5(6):1041-52. doi: 10.1016/0306-4522(80)90185-2.

Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ. V. Qualitative correlation between pharmacological effects and equilibration processes of the cholinergic receptor protein as revealed by the structural probe quinacrine.

J Mol Biol. 1976 Sep 25;106(3):517-35. doi: 10.1016/0022-2836(76)90250-3.

Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata.

Eur J Biochem. 1979 Feb 15;94(1):255-79. doi: 10.1111/j.1432-1033.1979.tb12893.x.

[Purification of a protein binding quinacrine and histrionicotoxin from membrane fragments rich in cholinergic receptors in Torpedo marmorata].[从电鳐富含胆碱能受体的膜片段中纯化结合喹吖因和组氨酰毒的蛋白质]

C R Acad Hebd Seances Acad Sci D. 1977 Nov 21;285(14):1255-8.

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J Biol Chem. 2012 Nov 23;287(48):40207-15. doi: 10.1074/jbc.R112.407668. Epub 2012 Oct 4.

Kinetics of agonist-induced intrinsic fluorescence changes in the Torpedo acetylcholine receptor.激动剂诱导的河豚乙酰胆碱受体固有荧光变化动力学。

J Biochem. 2010 May;147(5):743-9. doi: 10.1093/jb/mvq007. Epub 2010 Jan 31.

Activation and desensitization of Torpedo acetylcholine receptor: evidence for separate binding sites.电鳐乙酰胆碱受体的激活与脱敏：不同结合位点的证据。

Proc Natl Acad Sci U S A. 1982 Nov;79(22):6757-61. doi: 10.1073/pnas.79.22.6757.

Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.完整神经肌肉接头中乙酰胆碱相互作用的动力学参数。

Proc Natl Acad Sci U S A. 1981 Nov;78(11):7200-4. doi: 10.1073/pnas.78.11.7200.

Time-resolved photolabeling by the noncompetitive blocker chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations.

Proc Natl Acad Sci U S A. 1984 Mar;81(6):1897-901. doi: 10.1073/pnas.81.6.1897.

Acetylcholine receptor kinetics.乙酰胆碱受体动力学

J Membr Biol. 1981 Feb 28;58(3):161-74. doi: 10.1007/BF01870902.

End-plate channel opening and the kinetics of quinacrine (mepacrine) block.终板通道开放与喹吖因（米帕林）阻断的动力学

J Physiol. 1980 Sep;306:283-306. doi: 10.1113/jphysiol.1980.sp013397.

Quinacrine (mepacrine) action at frog end-plate.喹吖因（米帕林）对蛙终板的作用。

J Physiol. 1980 Sep;306:261-81. doi: 10.1113/jphysiol.1980.sp013396.

Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators.烟碱型乙酰胆碱受体的脱敏：分子机制及调节剂的作用

Cell Mol Neurobiol. 1989 Jun;9(2):141-78. doi: 10.1007/BF00713026.

Effects of chlorpromazine and phencyclidine on mouse C2 acetylcholine receptor kinetics.氯丙嗪和苯环己哌啶对小鼠C2乙酰胆碱受体动力学的影响。

J Physiol. 1986 Sep;378:497-513. doi: 10.1113/jphysiol.1986.sp016232.

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