Testa J R, Fukuda Y, Kowalski L P
Department of Otolaryngology, Universidade Federal de São Paulo, Brazil.
Arch Otolaryngol Head Neck Surg. 1997 Jul;123(7):720-4. doi: 10.1001/archotol.1997.01900070064010.
Carcinomas of the external auditory canal are rare neoplasms (< 1% of all head and neck malignant neoplasms).
To evaluate the prognostic factors in 79 patients treated in a single institution.
The disease was staged as follows: 34 patients with stage T1 to T2 tumors; 43 patients with stage T3 to T4 tumors; 2 patients with stage TX tumors; 68 patients with stage N0 tumors; and 11 patients with stage N1 tumors. The initial treatment was surgery in 59 patients and radiotherapy in 9 patients. Eleven patients were not considered candidates for treatment.
To date, 29 patients have experienced local recurrences and 2, neck metastases. The 5-year survival rates were 65% for patients who underwent surgery, 29% for patients who underwent radiotherapy, and 63% for patients who underwent a combination of surgery and radiotherapy. Univariate survival analysis showed statistical difference according to tumor type (P = .003), bone involvement (P = .002), and tumor stage (P < .001).
Every effort must be undertaken to make an early diagnosis and perform radical surgical resection of squamous cell carcinomas in the external auditory canal. This study validates the staging system used for squamous cell carcinoma of the ear treated with surgery.
外耳道癌是罕见肿瘤（占所有头颈部恶性肿瘤的比例不到1%）。
评估在单一机构接受治疗的79例患者的预后因素。
疾病分期如下：34例T1至T2期肿瘤患者；43例T3至T4期肿瘤患者；2例TX期肿瘤患者；68例N0期肿瘤患者；11例N1期肿瘤患者。初始治疗中59例患者接受手术，9例患者接受放疗。11例患者未被视为治疗候选者。
迄今为止，29例患者出现局部复发，2例出现颈部转移。接受手术的患者5年生存率为65%，接受放疗的患者为29%，接受手术联合放疗的患者为63%。单因素生存分析显示，根据肿瘤类型（P = .003）、骨质受累情况（P = .002）和肿瘤分期（P < .001）存在统计学差异。
必须尽一切努力对外耳道鳞状细胞癌进行早期诊断并实施根治性手术切除。本研究验证了用于接受手术治疗的耳部鳞状细胞癌的分期系统。
