Connelly T J, Kowalcyk A P
Connelly Skin Cancer Surgery Center, Stuarl, FL 34994, USA.
Dermatol Surg. 1997 Jul;23(7):588-90. doi: 10.1111/j.1524-4725.1997.tb00695.x.
Merkel cell (neuroendocrine) carcinoma (MCC) is a very aggressive primary cutaneous neoplasm most often occurring on the head and neck of the elderly. Spontaneous regression of MCC was first described in this journal in 1986. Since then, other such cases have been reported. This case represents the sixth case of spontaneous regression of MCC.
To describe to clinical course in a patient with MCC who underwent spontaneous regression of metastatic disease.
Clinical records including detailed history and frequent follow-up examination made this observation possible.
Complete clinically evident regression of metastatic MCC was observed in this case. However, the patient received no treatment known to be effective for MCC.
Spontaneous regression of MCC has been documented. The reason for regression is unknown. Further study of these rare cases may in the future provide more answers than questions.
默克尔细胞（神经内分泌）癌（MCC）是一种极具侵袭性的原发性皮肤肿瘤，最常发生于老年人的头颈部。MCC的自发消退于1986年首次在本杂志上被描述。自那时起，其他此类病例也有报道。本病例是MCC自发消退的第六例。
描述一例发生转移性疾病自发消退的MCC患者的临床病程。
包括详细病史和频繁随访检查的临床记录使该观察成为可能。
本病例中观察到转移性MCC在临床上完全消退。然而，该患者未接受任何已知对MCC有效的治疗。
MCC的自发消退已有记录。消退原因尚不清楚。对这些罕见病例的进一步研究未来可能会提供更多答案而非问题。
