Vukas A
Dermatologica. 1977;155(6):355-61. doi: 10.1159/000250992.
Our procedure for treating psoriatic variants--psoriasis pustulosa generalisata (PPG) and psoriasis erythrodermica (PE)--was based on the following points: (a) to quickly obtain a good tolerance level to photochemotherapy (PUVA) by applying corticosteroids and/or methotrexate (MX); (b) to discontinue the application of systemic drugs with the help of photochemotherapy, and (c) to maintain the improved condition by applying radiation in gradually prolonged intervals, thus enabling the biologic forces of the organism to participate, undisturbed by drugs, in the healing process. In some PE cases, sole PUVA therapy was sufficient, while in others small doses of MX were added to maintain the improved condition. In PPG, skin manifestations completely disappeared and general symptoms were calmed in the first application of this combined therapeutic procedure. However, in the later relapses PUVA had little share in such a combined treatment.
我们治疗银屑病变体——泛发性脓疱型银屑病（PPG）和红皮病型银屑病（PE）的程序基于以下几点：（a）通过应用皮质类固醇和/或甲氨蝶呤（MX）快速获得对光化学疗法（PUVA）的良好耐受水平；（b）借助光化学疗法停用全身药物；（c）通过逐渐延长间隔时间进行辐射来维持改善后的状况，从而使机体的生物力量能够不受药物干扰地参与愈合过程。在一些PE病例中，单纯PUVA疗法就足够了，而在其他病例中则添加小剂量的MX以维持改善后的状况。在PPG中，在首次应用这种联合治疗程序时，皮肤表现完全消失，全身症状得到缓解。然而，在后来的复发中，PUVA在这种联合治疗中作用不大。
