Santoli C, Respighi E, De Gasperis C, Pellegrini A
G Ital Cardiol. 1977;7(9):877-87.
Nineteen patients with ventricular septal defect (V.S.D) and valvular aortic insufficiency (A.I.), who underwent surgical repair, were reported. In the majority of patients the V.S.D. was localized in the supracristal region and the most frequent aortic valve abnormality was a prolapsing right cusp. Closure of the V.S.D. was effected with a patch in 15 patients and by direct suture in 4. Surgical management of A.I. consisted of: a) replacement of the aortic valve in 12 patients; b) no procedure on the aortic valve in 6 patient; c) plastic repair of the aortic valve in 1 patient. Only one patient died. Conservative management of the A.I. is advocated, but this is possible only if early repair is attempted. In adults, replacement with a prosthesis is indicated for severe A.I.
报告了19例患有室间隔缺损（V.S.D）和瓣膜性主动脉瓣关闭不全（A.I.）并接受手术修复的患者。大多数患者的室间隔缺损位于嵴上区域，最常见的主动脉瓣异常是右瓣叶脱垂。15例患者用补片关闭室间隔缺损，4例通过直接缝合关闭。主动脉瓣关闭不全的手术治疗包括：a）12例患者置换主动脉瓣；b）6例患者未对主动脉瓣进行手术；c）1例患者对主动脉瓣进行整形修复。仅1例患者死亡。主张对主动脉瓣关闭不全进行保守治疗，但这只有在尝试早期修复时才有可能。在成人中，对于严重的主动脉瓣关闭不全，建议使用人工瓣膜置换。
