Hahn K A, McGavin M D, Adams W H
Vet Pathol. 1997 Jul;34(4):352-5. doi: 10.1177/030098589703400413.
Chondrosarcoma is the most common nonepithelial sinonasal neoplasm in the dog, and metastasis is considered rare. A 7-year-old Irish Setter had bilateral renal enlargement 17 months following surgery and radiotherapy for a primary nasal chondrosarcoma. Histologic evaluation revealed chondrosarcoma metastases in both kidneys. A diagnosis of nasal chondrosarcoma with bilateral renal metastasis was made. The clinical importance of this report is that routine recommendations for the evaluation of regional and/or distant metatasis in a dog with a dignosis of nasal chondrosarcoma, namely routine whole body physical examination and thoracic radiography, failed to demonstrate the presence of abdominal metatases, which ultimately led to the demise of this dog. The biologically aggressive nature of this chondrosarcoma of the nasal cavity indicates that additional information is needed before a prognosis can be reliably established for dogs with this tumor type.
软骨肉瘤是犬类最常见的非上皮性鼻窦肿瘤，且转移被认为较为罕见。一只7岁的爱尔兰赛特犬在接受原发性鼻软骨肉瘤手术和放疗17个月后出现双侧肾脏肿大。组织学评估显示双侧肾脏均有软骨肉瘤转移。诊断为鼻软骨肉瘤伴双侧肾脏转移。本报告的临床意义在于，对于诊断为鼻软骨肉瘤的犬只，评估区域和/或远处转移的常规建议，即常规全身体格检查和胸部X线摄影，未能显示腹部转移的存在，这最终导致了这只犬的死亡。鼻腔软骨肉瘤的生物学侵袭性表明，在能够可靠地确定这种肿瘤类型犬只的预后之前，还需要更多信息。
