Limata C, Schoen E J, Cohen D, Black S B, Quesenberry C P
Department of Genetics, Kaiser Permanente Medical Care Program, Oakland, California 94611, USA.
J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Jun 1;15(2):126-30. doi: 10.1097/00042560-199706010-00005.
Results of a recent national clinical trial show that maternal-to-fetal transfer of HIV can be decreased threefold by prenatal, intrapartum, and neonatal treatment. The question is whether to make prenatal HIV testing compulsory or to encourage voluntary testing. Kaiser Permanente Northern California (KPNC), which has 2.5 million members, is part of a large health maintenance organization (HMO). In 1994, KPNC cared for 32,700 prenatal patients; 16,500 (50%) agreed to voluntary HIV testing. Compliance with testing ranged from 0% to 92% among the 31 KPNC locations. A study done by telephone survey identified three main factors favoring success of voluntary HIV screening: the ease and accessibility of HIV testing, a designated educator, and the presence of a registered nurse on the counseling team. In 1995, following feedback to the 31 facilities of the 1994 results, compliance rose to 19,800 of 31,300 prenatal patients (63%). KPNC, by encouraging counseled voluntary screening and following known positive cases, hopes to identify, track, and offer treatment options to all HIV-positive prenatal patients.
最近一项全国性临床试验的结果表明,通过产前、产时和新生儿治疗,母婴间的艾滋病毒传播可减少两倍。问题在于,是强制进行产前艾滋病毒检测,还是鼓励自愿检测。北加利福尼亚州凯撒医疗集团(KPNC)拥有250万会员,是一家大型健康维护组织(HMO)的一部分。1994年,KPNC为32700名产前患者提供护理;其中16500人(50%)同意进行自愿艾滋病毒检测。在KPNC的31个地点,检测的依从率从0%到92%不等。一项通过电话调查进行的研究确定了有利于自愿艾滋病毒筛查成功的三个主要因素:艾滋病毒检测的便捷性、指定的教育工作者以及咨询团队中有注册护士。1995年,在向31个机构反馈1994年的结果后,31300名产前患者中的19800人(63%)的检测依从率有所上升。KPNC通过鼓励接受咨询后的自愿筛查并跟踪已知的阳性病例,希望识别、追踪所有艾滋病毒呈阳性的产前患者并为其提供治疗选择。