Godowicz B
Folia Histochem Cytochem (Krakow). 1977;15(3):211-5.
Abnormal spermatozoa in mice of the KE strain, with defective chromatin condensation, are induced by disturbances in the process of spermiogenesis. When stained with methyl green-pyronin, spermatozoa with elongated heads reveal a staining pattern characteristic of the 13th stage of development of spermatids, indicating that they are not totally transformed molecularly, like normal spermatozoa. Labeling with L-arginine-5-H3 showed a weaker incorporation of arginine in the heads of the abnormal spermatozoa particularly those with elongated heads. Errors in the process of differentiation of spermatozoa leading to abnormal shapes may be related to atypical composition of deoxyribonucleoproteins (DNP).
KE品系小鼠的异常精子，染色质凝聚存在缺陷，是由精子发生过程中的干扰所诱导的。用甲基绿-派洛宁染色时，头部细长的精子呈现出精子细胞发育第13阶段特有的染色模式，这表明它们在分子层面上并未像正常精子那样完全转化。用L-精氨酸-5-H3标记显示，异常精子头部，尤其是头部细长的精子，精氨酸的掺入较弱。精子分化过程中导致异常形状的错误可能与脱氧核糖核蛋白（DNP）的非典型组成有关。
