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乳腺癌风险:首次足月妊娠早的保护作用与人工流产风险增加的对比

Breast cancer risk: protective effect of an early first full-term pregnancy versus increased risk of induced abortion.

作者信息

Canty L

机构信息

University of Incarnate Word, San Antonio, TX, USA.

出版信息

Oncol Nurs Forum. 1997 Jul;24(6):1025-31.

PMID:9243587
Abstract

PURPOSE/OBJECTIVES: To examine the question of whether an early first full-term pregnancy (FFTP) protects against breast cancer and whether interruption of the pregnancy with an induced abortion increases breast cancer risk.

DATA SOURCES

Published medical and epidemiology journal articles, books, scientific reports, news interviews of researchers, scientific journals.

DATA SYNTHESIS

Continually increasing breast cancer rates cannot be explained by the American Cancer Society risk factors, which account for only 25% of cases. Induced abortion is a newly recognized risk factor and has been prevalent in our society since it was legalized in 1973.

CONCLUSIONS

Early FFTP confers protection, while induced abortion confers risk. Most specific and controlled variables studies indicate 150% risk for abortions performed on women younger than 18 years of age. Studies have yet to discover the full impact of induced abortion because women who underwent legalized abortion in 1973 are just reaching ages of highest breast cancer incidence. IMPLICATIONS FOR NURSES: Awareness of a controversial risk factor and its relevance to women allows nurses to include this information when educating and supporting patients. Specifically, nurses need to include questions on this reproductive risk when eliciting a patient's reproductive history. Nurses should further be aware of the emotional impact disclosure may have.

摘要

目的/目标:探讨首次足月妊娠(FFTP)早是否能预防乳腺癌,以及人工流产导致的妊娠中断是否会增加乳腺癌风险。

数据来源

已发表的医学和流行病学杂志文章、书籍、科学报告、对研究人员的新闻采访、科学期刊。

数据综合

美国癌症协会的风险因素仅占乳腺癌病例的25%,无法解释乳腺癌发病率的持续上升。人工流产是一个新发现的风险因素,自1973年合法化以来在我们的社会中一直很普遍。

结论

早期首次足月妊娠具有保护作用,而人工流产则会带来风险。大多数特定且有对照变量的研究表明,18岁以下女性进行人工流产的风险为150%。由于1973年接受合法人工流产的女性刚刚达到乳腺癌发病率最高的年龄,研究尚未发现人工流产的全部影响。对护士的启示:意识到一个有争议的风险因素及其与女性的相关性,使护士在教育和支持患者时能够纳入这些信息。具体而言,护士在询问患者的生殖史时,需要包括关于这种生殖风险的问题。护士还应进一步意识到披露信息可能产生的情感影响。

相似文献

1
Breast cancer risk: protective effect of an early first full-term pregnancy versus increased risk of induced abortion.乳腺癌风险:首次足月妊娠早的保护作用与人工流产风险增加的对比
Oncol Nurs Forum. 1997 Jul;24(6):1025-31.
2
Does abortion increase the risk of breast cancer?堕胎会增加患乳腺癌的风险吗?
J Med Assoc Ga. 1994 Apr;83(4):209-10.
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Differences between spontaneous and induced abortions as risk factors for breast cancer.自然流产与人工流产作为乳腺癌风险因素的差异。
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Heightened risk of breast cancer following pregnancy: could lasting systemic immune alterations contribute?妊娠后乳腺癌风险增加:持续的全身免疫改变会是原因之一吗?
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Does induced or spontaneous abortion affect the risk of breast cancer?人工流产或自然流产会影响患乳腺癌的风险吗?
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Late effects of induced abortion. Hypothesis or knowledge?人工流产的远期影响。是假说还是知识?
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