Wolf S E, Debroy M, Herndon D N
Shriners Burns Institute, Galveston Unit and the University of Texas Medical Branch, Texas, USA.
Pediatr Surg Int. 1997 Jul;12(5-6):312-20. doi: 10.1007/BF01076929.
Active basic-science investigations and directed clinical research have resulted in effective therapies for improving the outcomes of burned children. Major areas of inquiry have been in resuscitation, hypermetabolism, wound coverage, and inhalation injury, all of which have yielded fruitful results. Probably the most important advance has been the widespread use of early excision and grafting, which has changed the pathophysiology of burn injury. Further advances in the fields of metabolism, wound healing, and respiratory medicine may improve results even further, particularily in functional and cosmetic outcomes.
积极的基础科学研究和定向临床研究已经产生了改善烧伤儿童治疗效果的有效疗法。主要研究领域包括复苏、高代谢、伤口覆盖和吸入性损伤，所有这些都取得了丰硕的成果。可能最重要的进展是早期切除和植皮的广泛应用，这改变了烧伤损伤的病理生理学。代谢、伤口愈合和呼吸医学领域的进一步进展可能会进一步改善治疗效果，特别是在功能和美容方面的效果。
