Menor F
Servicio de Radiodiagnóstico, Hospital Infantil La Fe, Valencia, España.
Rev Neurol. 1997 Jun;25(142):966-9.
Magnetic resonance imaging (MRI) exhibits a high sensitivity to detect white matter alteration but lacks specificity to characterize the disorder. We focus on the differential MR finding In two supposed autoimmune demyelinating diseases: multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM). In ADEM, the associated finding of T2 prolongation in deep gray matter, specially the thalamic involvement, is a useful distinguishing feature. Given that ADEM is usually a monophasic disease the lesional enhancement should be homogeneous, and new lesions would not be expected to occur in serial MRI. Advances in neuroimaging of myelin disorders are intended for improve the resolution and sensitivity of MRI and for research new techniques to quantify lesion load and to monitor demyelination and neuronal damage.
磁共振成像（MRI）在检测白质改变方面具有高灵敏度，但在明确疾病特征方面缺乏特异性。我们重点关注两种疑似自身免疫性脱髓鞘疾病：多发性硬化症（MS）和急性播散性脑脊髓炎（ADEM）的鉴别性磁共振成像表现。在ADEM中，深部灰质T2延长的相关表现，特别是丘脑受累，是一个有用的鉴别特征。鉴于ADEM通常是单相疾病，病变强化应均匀，并且在系列MRI检查中不应出现新的病变。髓鞘疾病神经影像学的进展旨在提高MRI的分辨率和灵敏度，并研发新技术以量化病变负荷以及监测脱髓鞘和神经元损伤。
