鼻咽癌组织提取物中尿激酶型纤溶酶原激活物（u-PA）和纤溶酶原激活物抑制剂-1（PAI-1）抗原的浓度。
The concentration of u-PA and PAI-1 antigen in tissue extracts of nasopharyngeal carcinoma.
作者信息
Sunagawa M, Huang G W, Nakamura M, Kosugi T
机构信息
1st Department of Physiology, School of Medicine, University of the Ryukyus, Okinawa, Japan.
出版信息
Eur Arch Otorhinolaryngol. 1997;254(6):277-80. doi: 10.1007/BF02905987.
We measured the antigen levels of urokinase-type plasminogen activator (u-PA) and plasminogen activator inhibitor-1 (PAI-1) in tissue extracts from nasopharyngeal carcinomas. An increase in u-PA antigen was observed with the advanced stages of disease. However, the levels of PAI-1 antigen decreased with each advanced stage. These results suggest that local administration of antiplasminic agents may be effective in suppressing tumor invasion.
我们检测了鼻咽癌组织提取物中尿激酶型纤溶酶原激活物（u-PA）和纤溶酶原激活物抑制剂-1（PAI-1）的抗原水平。随着疾病进展，观察到u-PA抗原增加。然而，PAI-1抗原水平随疾病进展而降低。这些结果表明，局部给予抗纤溶药物可能有效抑制肿瘤侵袭。
Zotero 插件