抗菌药物的药效学及其给药原理。
Pharmacodynamics of antimicrobial agents and rationale for their dosing.
作者信息
MacGowan A P, Bowker K E
机构信息
Bristol Centre for Antimicrobial Research and Evaluation, Southmead Health Services NHS Trust, UK.
出版信息
J Chemother. 1997 May;9 Suppl 1:64-73.
PMID:9248964
Abstract
Antimicrobial pharmacodynamics are an area of considerable importance in terms of dose regimen optimisation and clinical outcome. The pharmacodynamic properties of penicillins, cephalosporins, carbapenems, quinolones, glycopeptides and aminoglycosides are reviewed; the impact such knowledge may have in the future on how we dose these agents is discussed.
摘要
就给药方案优化和临床结果而言，抗菌药物动力学是一个相当重要的领域。本文综述了青霉素类、头孢菌素类、碳青霉烯类、喹诺酮类、糖肽类和氨基糖苷类药物的药效学特性；并讨论了这些知识未来可能对我们如何给药这些药物产生的影响。
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