源自染色体分选DNA的大鼠5号染色体标记的定位
Mapping of rat chromosome 5 markers generated from chromosome-sorted DNA.
作者信息
Deng A Y, Jackson C M, Hoebee B, Rapp J P
机构信息
Department of Physiology and Molecular Medicine, Medical College of Ohio, 300 Arlington Ave., P.O. Box 10008, Toledo, Ohio, 43699-0008, USA.
出版信息
Mamm Genome. 1997 Aug;8(8):549-53. doi: 10.1007/s003359900501.
PMID:9250858
Abstract
Nineteen markers for rat Chromosome 5 (Chr) were generated by screening chromosome-sorted DNA libraries and were subsequently mapped by linkage to known markers by use of five F2 rat populations. Along with existing markers, these newly produced markers are potentially useful for fine mapping of certain quantitative trait loci for blood pressure and for obesity.
摘要
通过筛选染色体分选的DNA文库，生成了19个大鼠5号染色体（Chr）的标记，随后利用5个F2大鼠群体，通过与已知标记的连锁分析将这些标记进行了定位。连同现有的标记一起，这些新产生的标记对于血压和肥胖症某些数量性状位点的精细定位可能是有用的。
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