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从人和动物中分离出的空肠弯曲菌和结肠弯曲菌菌株的侵袭性和肠毒素特性。

Invasive and enterotoxic properties in Campylobacter jejuni and Campylobacter coli strains isolated from humans and animals.

作者信息

Fernández H, Trabulsi L R

机构信息

Instituto de Microbiología Clínica, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile.

出版信息

Biol Res. 1995;28(3):205-10.

PMID:9251750
Abstract

Invasive properties of 15 strains of thermotolerant Campylobacter (12 C. jejuni and 3 C. coli) were studied using HeLa cells cultures. In four of them (3 C. jejuni and 1 C. coli), randomly selected, intestinal perfusion experiments were conducted in order to asses enterotoxigenicity. All strains were able to invade HeLa cells. The number of invaded HeLa cells ranged from 3 to 46%. In addition to their invasive properties, the 4 strains used in perfusion experiments were able to induce either a net secretory flux or an impaired sodium transport.

摘要

利用HeLa细胞培养研究了15株耐热弯曲杆菌(12株空肠弯曲杆菌和3株结肠弯曲杆菌)的侵袭特性。随机选择其中4株(3株空肠弯曲杆菌和1株结肠弯曲杆菌)进行肠道灌注实验,以评估其产肠毒素能力。所有菌株均能侵袭HeLa细胞。侵袭HeLa细胞的数量在3%至46%之间。除了具有侵袭特性外,灌注实验中使用的4株菌株能够诱导净分泌通量或钠转运受损。

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