Selinger J V, Schnur J M
Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375, USA.
Biophys J. 1997 Aug;73(2):966-71. doi: 10.1016/S0006-3495(97)78129-3.
We present a theory for cooperative chiral order in the transition between right-handed B-DNA and left-handed Z-DNA. This theory, based on the random-field Ising model, predicts the characteristic length scale of Z-DNA segments. This length scale depends on whether the DNA is a homopolymer or a random sequence: it is approximately 4000 nucleotides in a homopolymer but only approximately 25 nucleotides in a random sequence. These theoretical results are consistent with experiments on DNA homopolymers and random sequences.
我们提出了一种关于右手B-DNA与左手Z-DNA转变过程中协同手性序的理论。该理论基于随机场伊辛模型，预测了Z-DNA片段的特征长度尺度。这个长度尺度取决于DNA是同聚物还是随机序列：在同聚物中约为4000个核苷酸，而在随机序列中仅约为25个核苷酸。这些理论结果与关于DNA同聚物和随机序列的实验结果一致。
