Petersen C, Goetz A, Bürger D, Mildenberger H
Department of Pediatric Surgery, Medical School Hannover, Germany.
J Pediatr Gastroenterol Nutr. 1997 Aug;25(2):204-9. doi: 10.1097/00005176-199708000-00013.
Acute and chronic pancreatitis in children differ from that in adults both from the etiology and the therapeutic approach. Within the frame of a blunt abdominal trauma-the most frequent cause in children-acute pancreatitis is often detected by emergency laparotomy and external drainage is recommended. Chronic relapsing pancreatitis, and particularly its hereditary form, is very rare in children and requires a different therapeutic concept. The results of surgical therapy for both forms of pancreatitis in childhood were evaluated in the present study.
Sixteen patients with acute and chronic relapsing pancreatitis were operated on in our facility between 1976 and 1988. Their history and postoperative course were analyzed in a retrospective study, including a final examination at the end of the follow-up period.
Eight children with acute pancreatitis were operated on at an average age of 6 years and were followed up for an average of 7.5 years, with good results. The remaining children, aged between 3 and 14 years (average age of 9 years), were operated on for chronic relapsing pancreatitis. Our experience with early operative treatment, on average 2.7 years after onset of symptoms, is presented. Only three patients experienced a mild relapse during the follow-up period of 2-13 years (average of 5.4 years).
For acute pancreatitis in childhood, operative treatment by inner drainage is necessary and effective only in case of complications, should conservative treatment fail. In children with chronic relapsing pancreatitis, the good exocrine and the normal endocrine function of the pancreas in these patients justified the early operation. Timely treatment is recommended in cases with typical changes of the pancreatic duct so as to shorten the relapsing clinical problems of the children and to maintain the function of the pancreas.
儿童急慢性胰腺炎在病因和治疗方法上均与成人不同。在钝性腹部创伤(儿童中最常见的病因)情况下,急性胰腺炎常通过急诊剖腹手术被发现,建议进行外引流。慢性复发性胰腺炎,尤其是其遗传性形式,在儿童中非常罕见,需要不同的治疗理念。本研究评估了儿童期两种形式胰腺炎的手术治疗结果。
1976年至1988年间,我们机构对16例急慢性复发性胰腺炎患者进行了手术。在一项回顾性研究中分析了他们的病史和术后病程,包括随访期结束时的最终检查。
8例急性胰腺炎患儿接受手术时的平均年龄为6岁,平均随访7.5年,效果良好。其余患儿年龄在3至14岁之间(平均年龄9岁),因慢性复发性胰腺炎接受手术。介绍了我们在症状出现后平均2.7年进行早期手术治疗的经验。在2至13年(平均5.4年)的随访期内,只有3例患者出现轻度复发。
对于儿童急性胰腺炎,仅在保守治疗失败且出现并发症的情况下,内引流手术治疗才是必要且有效的。对于慢性复发性胰腺炎患儿,这些患者胰腺良好的外分泌和正常的内分泌功能证明了早期手术的合理性。对于胰管有典型变化的病例,建议及时治疗,以缩短患儿临床复发问题并维持胰腺功能。