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大脑胆碱能系统在分离学习机制中的作用研究。

Studies of the role of the brain cholinergic system in the mechanisms of dissociative learning.

作者信息

Azarashvili A A

机构信息

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino.

出版信息

Neurosci Behav Physiol. 1997 Jul-Aug;27(4):341-6. doi: 10.1007/BF02462933.

DOI:10.1007/BF02462933
PMID:9252989
Abstract

Rats were trained to make conditioned food reflex excursions in two states: in normal conditions and on a background of treatment with pharmacological agents producing dissociative states. A number of cholinergic substances were completely interchangeable in dissociative learning; anticholinergic compounds efficiently neutralized the ability of cholinergic substances to produce dissociative states; muscarinic cholinoreceptors played the leading role in production of the dissociative state.

摘要

大鼠被训练在两种状态下做出条件性食物反射动作

正常条件下以及在产生分离状态的药物治疗背景下。在分离学习中,多种胆碱能物质可完全互换;抗胆碱能化合物能有效中和胆碱能物质产生分离状态的能力;毒蕈碱型胆碱能受体在分离状态的产生中起主导作用。

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1
Studies of the role of the brain cholinergic system in the mechanisms of dissociative learning.大脑胆碱能系统在分离学习机制中的作用研究。
Neurosci Behav Physiol. 1997 Jul-Aug;27(4):341-6. doi: 10.1007/BF02462933.
2
[The role of the cholinergic system of the brain in the mechanisms of dissociated learning].[大脑胆碱能系统在分离学习机制中的作用]
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[Role of M- and N-cholinergic biosystems of the brain in the mechanisms responsible for optokinetic, postoptokinetic, and reversed postoptokinetic nystagmus].
Fiziol Zh SSSR Im I M Sechenova. 1981 May;67(5):738-43.
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引用本文的文献

1
The complex perception of stimuli during the acquisition of conditioned reflexes.条件反射形成过程中对刺激的复杂感知。
Neurosci Behav Physiol. 2002 May-Jun;32(3):247-53; discussion 253-4. doi: 10.1023/a:1015054122202.

本文引用的文献

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STATE-DEPENDENT OR "DISSOCIATED" LEARNING PRODUCED WITH PENTOBARBITAL.由戊巴比妥产生的状态依赖性或“分离性”学习。
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State-dependent learning produced by depressant and atropine-like drugs.由抑制剂和阿托品样药物产生的状态依赖学习。
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Experimental methods for the study of state-dependent learning.用于研究状态依存性学习的实验方法。
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Theoretical explanations of drug-dissociated behaviors.药物解离行为的理论解释。
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[The role of different neuromediator systems in regulating the reproduction of memory engrams in rats].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Nov-Dec;38(6):1107-12.
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[The effect of iproniazid on biogenic amine levels, elaboration and reproduction of alimentary conditioned reflexes].[异烟酰异丙肼对生物胺水平、食物性条件反射的形成与再现的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Jan-Feb;26(1):104-10.