Azarashvili A A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1996 Mar-Apr;46(2):309-16.
The mechanisms of dissociated learning in rats were studied with application on conditioning technique and pharmacological analysis of memory. Anticholinesterase drugs were shown to be interchangeable in inducing dissociated states in learning. Anticholinergic substances completely neutralized the ability of cholinergic drugs that create dissociated states. It was shown that muscarinic cholinergic receptors largely contribute in inducing dissociated states. The findings well agree with the earlier author's hypothesis that the cholinergic brain system plays a decisive role in the mechanisms of dissociated learning.
运用条件反射技术和记忆的药理学分析方法，对大鼠分离学习的机制进行了研究。结果表明，抗胆碱酯酶药物在诱导学习中的分离状态方面具有可互换性。抗胆碱能物质完全抵消了能产生分离状态的胆碱能药物的作用。研究表明，毒蕈碱胆碱能受体在诱导分离状态中起主要作用。这些发现与作者早期的假设高度一致，即胆碱能脑系统在分离学习机制中起决定性作用。
