Voiculescu C, Voiculescu M, Avramescu C, Radu E
Faculty of Medicine, Department of Microbiology and Immunology, Craiova, Romania.
Roum Arch Microbiol Immunol. 1996 Apr-Jun;55(2):107-17.
115 patients with non-immune (IgE-negative) urticaria, related to parasitic (lambliasis, oxyuriasis, ascaridiasis) or fungal (candidiasis) associations were investigated-both before and one month after specific and antihistaminic therapy-concerning different percentage levels of blood lymphocyte sets and subsets, by means of flow cytometry. Before therapy, three kinds of immune deficiency patients were obtained, one in lambliasis and oxyuriasis, the second in ascaridiasis, and the third in candidiasis, respectively. Clinical, biological and immunological recovering after therapy exhibited some differences related to the presumed non-allergic etiology, i.e. better in lambliasis and oxyuriasis and worse in ascaridiasis and candidiasis.
对115例与寄生虫(贾第虫病、蛲虫病、蛔虫病)或真菌(念珠菌病)相关的非免疫性(IgE阴性)荨麻疹患者,在特异性治疗和抗组胺治疗前及治疗后1个月,通过流式细胞术研究了不同百分比水平的血液淋巴细胞群和亚群。治疗前,分别在贾第虫病和蛲虫病、蛔虫病、念珠菌病患者中发现了三种免疫缺陷类型。治疗后的临床、生物学和免疫学恢复情况因假定的非过敏性病因有所不同,即贾第虫病和蛲虫病患者恢复较好,蛔虫病和念珠菌病患者恢复较差。